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                            CALL FOR PAPERS
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                 Journal of Combinatorial Optimization

                             Special Issue on
                     Computational Molecular Biology


Guest Editors:       Ying Xu, Satoru Miyano, Tom Head.

Submission Deadline: August 15, 1998.


The past ten years have witnessed the rapid development of a new discipline,
computational molecular biology.  Combinatorial optimization and algorithms
have played a significant role in advancing this new discipline.  The
partnership between mathematics, in particular combinatorial optimization and 
algorithms, and molecular biology has greatly enriched both fields, leading
to new ways of thinking and greater challenges to meet. 

The scope of this Special Issue includes all aspects of combinatorial
optimization and algorithms in computational molecular biology.  Original
papers are solicited that describe research on combinatorial methods for
problems arising from the following areas (nonexhaustive) of molecular biology:

           -- DNA sequencing
           -- DNA mapping
           -- recognition of genes and regulatory elements
           -- RNA/protein structure prediction 
           -- molecular evolution
           -- combinatorial libraries and drug design
           -- bio-sequence analysis and comparison
           -- computing with biomolecules.

Six hard copies of each submitted manuscript should be sent to one of the
guest editors by August 15, 1998. Manuscripts must be prepared according to
the normal submission requirements of the Journal of Combinatorial Optimization

(see <http://www.wkap.nl/journalhome.htm/1382-6905>). 

Each manuscript will be refereed by at least three anonymous reviewers.
Notification of acceptance willbe sent to the authors before November 30,
1998. The Special Issue is expected to be published by mid-1999.

Addresses of the guest editors:

              Ying Xu
              Computational Biosciences Section
              Building 1060 COM
              Oak Ridge National Laboratory
              Oak Ridge, TN 37831-6480, USA
              Tel: 423-574-3783 
              Fax: 423-241-1965
              Email: xyn@ornl.gov
              Web: <http://compbio.ornl.gov/~xyn/>

              Satoru Miyano
              Human Genome Center
              Institute of Medical Science
              University of Tokyo
              Shirokanedai 4-6-1, Minato-ku, Tokyo 108-8639,
              Japan.
              Tel.: +81-3-5449-5615
              Fax: +81-3-5449-5442 
              Email: miyano@ims.u-tokyo.ac.jp

              Tom Head
              Department of Mathematics
              Binghamton University
              Binghamton, NY 13902-6000, USA
              Tel: 607-777-2278
              Fax: 607-777-2450
              Email: tom@math.binghamton.edu
              Web: <http://math.binghamton.edu/tom/index.html>